- RESEARCH USE ONLY
- INDEPENDENTLY THIRD-PARTY TESTED
- COA EVERY LOT
- US-BASED OPERATIONS
| Specification | Details |
|---|---|
| Compound | Thymosin Alpha-1 |
| Alternative Name | Thymalfasin / Tα1 |
| Type | Synthetic 28-amino-acid peptide |
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH |
| Quantity | 5 mg |
| Purity | ≥99% HPLC Certified |
| Molecular Formula | C₁₂₉H₂₁₅N₃₃O₅₅ |
| Molecular Weight | ~3108.3 g/mol |
| CAS Number | 69521-94-4 / 62304-98-7 |
| Form | Lyophilized powder |
| Appearance | White to off-white powder |
| Solubility | Soluble in laboratory-grade sterile water |
| Documentation | COA included in product image gallery |
$44.99
For Research Use Only | Not for Human or Veterinary Use
Thymosin Alpha-1 (Tα1), also known as thymalfasin, is a synthetic 28-amino-acid peptide corresponding to an acetylated sequence originally isolated from thymic tissue. Its defined sequence is SDAAVDTSSEITTKDLKEKKEVVEEAEN, with N-terminal acetylation.
Research on Thymosin Alpha-1 has examined peptide interactions with components of innate and adaptive immune signaling, including experimental work involving antigen-presenting cells, cytokine signaling, and toll-like receptor pathways. These findings come from biochemical, cellular, animal, and clinical research conducted for specific scientific questions and should not be presented as established effects of a research-grade material.
This material is supplied as a lyophilized powder for laboratory research, analytical testing, and related scientific applications.
PubChem lists Thymalfasin with molecular formula C₁₂₉H₂₁₅N₃₃O₅₅ and CAS identifiers including 69521-94-4 and 62304-98-7. Published analytical work reports a molecular weight of approximately 3108 Da for the acetylated 28-residue peptide.
Thymosin Alpha-1 was first isolated from calf thymic tissue and subsequently characterized as a 28-amino-acid peptide. Its N-terminal acetylation is part of the molecular structure and is represented in the sequence as Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH.
Experimental research has investigated Tα1 in relation to immune-cell signaling and innate immune pathways. Studies have examined interactions involving antigen-presenting cells and toll-like receptor signaling, including work using cellular and animal models.
Because Tα1 has been studied across several experimental systems, individual findings should be interpreted according to the model, peptide preparation, concentration, and experimental conditions used rather than generalized across all research applications.
The supplied material is specified at ≥99% HPLC Certified purity, with a Certificate of Analysis included in the product image gallery.
Researchers should review the batch-specific COA for the reported purity, molecular identity, and analytical information before incorporating the material into laboratory workflows.
For acetylated Tα1, analytical identity can include sequence confirmation together with chromatographic and mass-spectrometric characterization. Published analytical work has demonstrated the use of LC-MS/MS to confirm the sequence of synthetic Tα1 preparations.
Thymosin Alpha-1 has been investigated internationally as thymalfasin, and the FDA has recorded several orphan-drug designations for the compound. These designations covered different proposed indications, but FDA records specify that the orphan designations were not FDA approvals.
FDA materials also distinguish orphan-drug designation from marketing approval and state that thymosin alpha-1 products are not approved by the FDA in the United States.
The material described on this page is therefore presented strictly as a laboratory research material and should not be represented as an FDA-approved pharmaceutical product.
Thymosin Alpha-1 contains 28 amino acid residues. Its defined sequence is SDAAVDTSSEITTKDLKEKKEVVEEAEN, with N-terminal acetylation.
The sequence is Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH. “Ac-” represents N-terminal acetylation, which forms part of the characterized peptide structure.
Thymalfasin is a name used for Thymosin Alpha-1. PubChem lists thymalfasin, alpha1-thymosin, and Thymosin Alpha-1 among the compound's associated names and identifiers.
The acetylated 28-residue peptide has a molecular weight of approximately 3108.3 g/mol. Published mass-spectrometric analysis has reported a value of approximately 3108 Da for synthetic Tα1.
No. They are different peptides with different sequences and molecular structures. Thymosin Alpha-1 is a 28-residue acetylated peptide, while thymosin beta-4 is a substantially longer 43-residue peptide.
No. FDA records document orphan-drug designations for thymalfasin, but those designations did not constitute FDA approval. FDA materials specifically distinguish these designations from marketing approval.
Thymosin Alpha-1 is supplied as a laboratory research material with HPLC-certified purity and batch-specific documentation available through the product gallery.
For Research Use Only | Not for Human or Veterinary Use
