SKU: MS10

MOTS-C

Specification Details
Compound Name MOTS-c
Full Name Mitochondrial Open Reading Frame of the 12S rRNA-c
Type Mitochondrial-Derived Peptide
Quantity 10 mg
Purity ≥99% (HPLC Certified)
Form Lyophilized Powder
Appearance White to Off-White Powder
Sequence MRWQEMGYIFYPRKLR
Molecular Formula C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular Weight 2,174.6 g/mol
CAS Number 1627580-64-6
COA Supplied With Each Batch

$59.99

For Research Use Only | Not for Human or Veterinary Use

Description

MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. It has been investigated in laboratory research involving cellular metabolic signaling and AMPK-related pathways.

This research material is supplied as a lyophilized powder with a stated purity of ≥99% by HPLC. A Certificate of Analysis (COA) is supplied with each batch for analytical reference.

The sequence, molecular formula, molecular weight, and CAS number correspond with established chemical reference information for human MOTS-c.

Research & Scientific Context

MOTS-c was identified as a short open reading frame within the mitochondrial 12S rRNA region that encodes a 16-amino-acid peptide. Early laboratory research examined its relationship with cellular metabolic processes and AMPK signaling.

Subsequent research has continued to examine MOTS-c in relation to metabolic signaling pathways and cellular responses under different experimental conditions. These findings are derived from specific laboratory and experimental models and should be interpreted within the context of the methods used in each study.

MOTS-c and WADA Status

MOTS-c is listed by the World Anti-Doping Agency (WADA) under S4.4.1 as an activator of AMP-activated protein kinase (AMPK). The 2026 WADA Prohibited List identifies MOTS-c by name under this category, which is prohibited at all times.

Analytical Documentation

The supplied product specification lists a purity of ≥99% by HPLC. High-Performance Liquid Chromatography (HPLC) is an analytical technique used to separate and characterize components within a sample.

A Certificate of Analysis is supplied with each batch and provides analytical information associated with the applicable material. Researchers can review the available documentation when evaluating the supplied research material.

Material Information

MOTS-c is supplied as a white to off-white lyophilized powder. Lyophilization is a controlled drying process used to prepare materials in a dry form for laboratory applications.

The product specification identifies laboratory-grade sterile water as a compatible solvent. Any material-specific handling or storage requirements should be reviewed against the applicable product documentation.

Frequently Asked Questions

1. What does MOTS-c stand for?

MOTS-c stands for mitochondrial open reading frame of the 12S rRNA-c, referring to the mitochondrial genomic region from which the peptide was identified.

2. What is the amino acid sequence of MOTS-c?

The reported 16-amino-acid sequence is MRWQEMGYIFYPRKLR. This sequence is listed in established chemical reference databases.

3. How many amino acids are in MOTS-c?

MOTS-c consists of 16 amino acids, making it a short mitochondrial-derived peptide.

4. What is the molecular weight of MOTS-c?

The reported molecular weight for MOTS-c is approximately 2,174.6 g/mol.

5. What is the CAS number for MOTS-c?

The CAS number listed for MOTS-c is 1627580-64-6.

6. Where can researchers review MOTS-c batch documentation?

The applicable Certificate of Analysis is supplied with each batch and can be reviewed for the analytical information associated with the material.

Research Materials & Documentation

Review the MOTS-c scientific specifications and applicable Certificate of Analysis when evaluating this material for laboratory research.